Endocrine Abstracts

IntroductionAs the incidence of pediatric obesity is increasing, so is the incidence of metabolic syndrome in the pediatric population. We present the management of 3 such cases.Case reportThree 14 (D.D), 15 (C.A.), 16 (C.M) year-old males presented for weight and metabolic management.DD had a medical history weight gain since 2 years old, obesity, dyslipidemia, hyperuricemia. C.A., obese since 2018, with hyp...

Introduction: Obesity and vitamin D deficit are risk factors for inflammation, insulin resistance, hypertension and impeded bone mineralization and also cardiovascular disease. type 2 diabetes and osteoporosis. As globally both conditions reach pandemic levels and the level of vitamin D negatively correlates with obesity we studied this correlation and impact on a group of children suffering from obesity.Materials and method: We conducted a retrospective...

Introduction: We report a case of papillary thyroid carcinoma recurrence. According to most of the guidelines, patients with PTC have recurrences in the first 5 years after diagnosis and the most rigorous follow-up is indicated in this time; however metastasis are reported beyond this period and are associated mostly with lack of adherence to follow-up.Case report: A 76-year-old female was admitted in our department for the evaluation of a 5 cm laterocer...

Introduction: We report a case of severe osteoporosis with incident fragility fractures during antiresorbtive therapy in the presence of amiodarone induced hypothyroidism.Case report: A 76 year old female was admitted in our department for the evaluation of antiresorbtive therapy in the context of a recent rib fracture after coughing. Severe osteoporosis (lumbar T-score: −2.8DS, femoral neck T-score: −2.9DS with multiple fra...

Introduction: As the incidence of thyroid cancer is increasing, so are the cases of recurrence with RAI refractory metastasis of thyroid differentiated cancer. We present such a caseCase report: A 77-year-old female with a medical history of papillary thyroid carcinoma recurrence 10 years after surgery with successful 3 RAI sessions and normal thyroid cancer markers after treatment until her recurrence a year ago, with TSH unstimulated thyroglobulin of 1...

Introduction: Duchenne muscular dystrophy (DMD) is a genetic condition caused by mutations in the X-linked dystrophin-gene leading to muscle degeneration and early death in males.Since DMD is characterized by aggressive inflammation it is recommended the use of pharmacological treatment with corticosteroids (CS). Type-1 diabetes mellitus (T1DM) is one of the most common chronic diseases in childhood and is caused by insulin deficiency resulting from the autoimmune destruction ...

Introduction: Neurofibromatosis type 1 (NF1) is the most common type of NF, and accounts for about 90% of all cases. Primary empty sella syndrome (ESS) results from herniation of arachnoid mater into the pituitary fossa. Since it has been demonstrated that the small anterior pituitary size reflects loss of neurofibromin expression in the hypothalamus, leading to reduced GHRH, pituitary GH and IGF1 production, we agree that IGF1 and GH increased in our patient can be challengin...

Introduction: The FRAX fracture risk assessment algorithm is able to integrate clinical risk factors independent of bone mineral density (BMD), evaluating the 10-years probability of fracture, therefore identifying patients in need for antiosteoporotic treatment, in which case bypassing the WHO (World Health Organization) criteria for densitometric diagnosis of osteoporosis.Material and Methods: We retrospectively analysed a total of 91 scans of women ag...